Dual Channel Sample Cleanup

From LEAP

Revision as of 13:56, 9 June 2009 by Bpeat (Talk | contribs)
Jump to: navigation, search

General Description of process:

Samples are injected and pass through a guard column which is in-line with the analytical column. At a specified time, the guard column switches out of line and is regenerated using a wash pump configured to do a step gradient while the sample peaks are acquired.

To increase throughput, samples are injected ahead of the acquisition time, so that pre-filtration is occurring concurrently with the previous samples acquisition. Each line of the sample list processes a pair of samples which are staggered in this way.

4 pumps are required: - 2 wash pumps (Agilent 1200) pre-programmed to perform the step gradient and 2 isocratic analytical pumps running continuously one for each column.


Image:Dual_Channel_Sample_Filtration_PlumbDiag.png


Project Ref: H1073b


For other cost/time saving measures consider:

  • LEAP offers multiple choices of Valve Self Wash Stations to aid in cleaning the valve [1]
  • “Look Ahead”, sample prep before injection (M-004) using LEAP Shell Software [2]
  • Dual Channel Parallel Injection (M-005) using LEAP Shell software [3]
  • Summary of LC Multi Valve Applications [4]
  • LEAP Shell Software and application for custom injections and scheduling [5]

Contact LEAP

For additional information about this technique please contact LEAP Technologies for detailed information

Contact the LEAP office

Personal tools