Dual Channel Sample Cleanup

From LEAP

Revision as of 03:11, 2 June 2009

General Description of process:

Samples are injected and pass through a guard column which is in-line with the analytical column. At a specified time, the guard column switches out of line and is regenerated using a wash pump configured to do a step gradient while the sample peaks are acquired.

To increase throughput, samples are injected ahead of the acquisition time, so that pre-filtration is occurring concurrently with the previous samples acquisition. Each line of the sample list processes a pair of samples which are staggered in this way.

4 pumps are required: - 2 wash pumps (Agilent 1200) pre-programmed to perform the step gradient and 2 isocratic analytical pumps running continuously one for each column.

Project Ref: H1073b

For other cost/time saving measures consider:

• LEAP offers multiple choices of Valve Self Wash Stations to aid in cleaning the valve [1]
• “Look Ahead”, sample prep before injection (M-004) using LEAP Shell Software [2]
• Dual Channel Parallel Injection (M-005) using LEAP Shell software [3]
• Summary of LC Multi Valve Applications [4]
• LEAP Shell Software and application for custom injections and scheduling [5]

leaptec.com
leapwiki.com

Contact LEAP

For additional information about this technique please contact LEAP Technologies for detailed information

• Contact the LEAP office