M-006 & M-007 In-Line Sample Concentration or Filtration
From LEAP
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| + | [[image: Info icon.png|40px]] [http://www.leapwiki.com/mediawiki/index.php?title=On-line_SPE_LC/MS/MS_to_Detect_Organonitrogen_and_Triazine_Pesticides_in_Drinking_Water On-Line SPE Application Note from ABI for Pesticides in Drinking Water] | ||
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| + | <br> | ||
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| + | === Overview === | ||
| + | This configuration allows the automated on-line Solid Phase Extraction (SPE). This is run directly from within '''Analyst Software'''[https://products.appliedbiosystems.com/ab/en/US/adirect/ab?cmd=catNavigate2&catID=600927&tab=DetailInfo] from ''Applied Biosystems Inc'' using a Standard LEAP Cycle (requires ICC-CE software) [http://www.leaptec.com/products/lc-related-instruments-and-accessories/ctc-lc-pal-software/instrument-control-components-and-cycle-editor-181.php]. | ||
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| + | There are 2 pumps needed, one for the gradient run and another (higher flow rate and isocratic) for regeneration [http://leapwiki.com/mediawiki/index.php?title=Category:Regeneration]. This configuration requires a TrioVS Valve [http://www.leaptec.com/products/lc-related-instruments-and-accessories/rotors-and-inlet-sleeves/pal-trio-vs--valve-system--80.php]. All of the valves must be controlled by the Standard LEAP cycle. <br> ''LEAP can not control the MS Selector valve as part of the cycle.'' | ||
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| + | [[Image:Empty TRIO.png|left frame|TrioVS valve is used. Flow path intentionally left incomplete. Contact LEAP for more information]] | ||
| + | <br> | ||
| + | [[Image:HTC_with_TRIO.png]] | ||
| + | <br> | ||
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| + | === Useful links === | ||
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| + | [[Image:Www icon.png|40px]] [http://www3.appliedbiosystems.com/cms/groups/applied_markets_marketing/documents/generaldocuments/cms_043785.pdf www.appliedbiosystems.com '''Application Note''' ] | ||
| + | <br><br> | ||
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| + | [[Image:Www icon.png|40px]] [http://www.leapwiki.com/mediawiki/index.php?title=On-line_SPE_LC/MS/MS_to_Detect_Organonitrogen_and_Triazine_Pesticides_in_Drinking_Water On-line Solid Phase Extraction (SPE) coupled to Liquid Chromatography with tandem Mass Spectrometry (LC/MS/MS) to detect organonitrogen and triazine pesticides at concentrations of 10ng/L in drinking water.] | ||
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=== For other cost/time saving measures consider:=== | === For other cost/time saving measures consider:=== | ||
* LEAP offers multiple choices of Valve Self Wash Stations to aid in cleaning the valve [http://www.leapwiki.com/mediawiki/index.php?title=Valve_Washing] | * LEAP offers multiple choices of Valve Self Wash Stations to aid in cleaning the valve [http://www.leapwiki.com/mediawiki/index.php?title=Valve_Washing] | ||
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| + | [[Image:LEAP Logo.png|frame|[http://www.leaptec.com leaptec.com]<br />[http://www.leapwiki.com leapwiki.com]]] | ||
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| + | This workstation application is based on the CTC PAL X, Y, Z syringe only autosampler robot from LEAP Technologies. This extremely flexible, precise, and adaptable robotic platform is available in a variety of lengths and options depending on the requirements of your sample preparation and injections for your LC or GC requirements. Please contact LEAP Technologies on how we can help you get maximized throughput with flexible automation. | ||
=== Contact LEAP === | === Contact LEAP === | ||
| - | |||
| - | + | [[image:Contact_Info.png|40px]] [http://www.leaptec.com/contact-us.php Contact the LEAP office] | |
<br><br> | <br><br> | ||
| - | [[Category: | + | |
| + | [[Category:LC Multi Valve Applications]] | ||
Current revision
| In-Line Sample Concentration or Filtration |
| Application Type | |
| SPECIAL | |
| Application ID | |
| M-006 & M-007 | |
| Description | |
| In-Line Sample Cleanup |
| Code | Application | Control SW | Key Hardware | Key Benefits | Restrictions | GLP |
|---|---|---|---|---|---|---|
| M-006 | Inline Sample Concentration SPE Column regenerated during analytical extraction | Analyst with ICC-CE | * TrioVS | * Automated concentration and elution of sample on SPE column prior to separation on analytical column | * No "Look Ahead" * Can not prep samples ahead of analytical run | No |
| Code | Application | Control SW | Key Hardware | Key Benefits | Restrictions | GLP |
|---|---|---|---|---|---|---|
| M-007 | Inline Sample Filtration SPE Column regenerated during analytical extraction | Analyst with ICC-CE | * TrioVS | * Automated filtration of sample on cleanup column prior to separation on analytical column | * No "Look Ahead" * Can not prep samples ahead of analytical run | No |
On-Line SPE Application Note from ABI for Pesticides in Drinking Water
Contents |
Overview
This configuration allows the automated on-line Solid Phase Extraction (SPE). This is run directly from within Analyst Software[1] from Applied Biosystems Inc using a Standard LEAP Cycle (requires ICC-CE software) [2].
There are 2 pumps needed, one for the gradient run and another (higher flow rate and isocratic) for regeneration [3]. This configuration requires a TrioVS Valve [4]. All of the valves must be controlled by the Standard LEAP cycle.
LEAP can not control the MS Selector valve as part of the cycle.
Useful links
www.appliedbiosystems.com Application Note
For other cost/time saving measures consider:
- LEAP offers multiple choices of Valve Self Wash Stations to aid in cleaning the valve [5]
- Summary of LC Multi Valve Applications [6]
- LEAP Shell Software and application for custom injections and scheduling [7]
This workstation application is based on the CTC PAL X, Y, Z syringe only autosampler robot from LEAP Technologies. This extremely flexible, precise, and adaptable robotic platform is available in a variety of lengths and options depending on the requirements of your sample preparation and injections for your LC or GC requirements. Please contact LEAP Technologies on how we can help you get maximized throughput with flexible automation.
