M-006 & M-007 In-Line Sample Concentration or Filtration
From LEAP
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+ | === Overview === | ||
+ | This configuration allows the automated on-line Solid Phase Extraction (SPE). This is run directly from within '''Analyst Software'''[https://products.appliedbiosystems.com/ab/en/US/adirect/ab?cmd=catNavigate2&catID=600927&tab=DetailInfo] from ''Applied Biosystems Inc'' using a Standard LEAP Cycle (requires ICC-CE software) [http://www.leaptec.com/products/lc-related-instruments-and-accessories/ctc-lc-pal-software/instrument-control-components-and-cycle-editor-181.php]. | ||
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+ | There are 2 pumps needed, one for the gradient run and another (higher flow rate and isocratic) for regeneration [http://leapwiki.com/mediawiki/index.php?title=Category:Regeneration]. This configuration requires a TrioVS Valve [http://www.leaptec.com/products/lc-related-instruments-and-accessories/rotors-and-inlet-sleeves/pal-trio-vs--valve-system--80.php]. All of the valves must be controlled by the Standard LEAP cycle. <br> ''LEAP can not control the MS Selector valve as part of the cycle.'' | ||
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+ | [[Image:Empty TRIO.png|left frame|TrioVS valve is used. Flow path intentionally left incomplete. Contact LEAP for more information]] | ||
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=== For other cost/time saving measures consider:=== | === For other cost/time saving measures consider:=== | ||
* LEAP offers multiple choices of Valve Self Wash Stations to aid in cleaning the valve [http://www.leapwiki.com/mediawiki/index.php?title=Valve_Washing] | * LEAP offers multiple choices of Valve Self Wash Stations to aid in cleaning the valve [http://www.leapwiki.com/mediawiki/index.php?title=Valve_Washing] |
Revision as of 19:32, 2 June 2009
In-Line Sample Concentration or Filtration | |
Application Type | |
SPECIAL | |
Application ID | |
M-006 & M-007 | |
Description | |
In-Line Sample Cleanup |
Code | Application | Control SW | Key Hardware | Key Benefits | Restrictions | GLP |
---|---|---|---|---|---|---|
M-006 | Inline Sample Concentration SPE Column regenerated during analytical extraction | Analyst with ICC-CE | * TrioVS | * Automated concentration and elution of sample on SPE column prior to separation on analytical column | * No "Look Ahead" * Can not prep samples ahead of analytical run | No |
Code | Application | Control SW | Key Hardware | Key Benefits | Restrictions | GLP |
---|---|---|---|---|---|---|
M-007 | Inline Sample Filtration SPE Column regenerated during analytical extraction | Analyst with ICC-CE | * TrioVS | * Automated filtration of sample on cleanup column prior to separation on analytical column | * No "Look Ahead" * Can not prep samples ahead of analytical run | No |
On-Line SPE Application Note from ABI for Pesticides in Drinking Water[1]
Overview
This configuration allows the automated on-line Solid Phase Extraction (SPE). This is run directly from within Analyst Software[2] from Applied Biosystems Inc using a Standard LEAP Cycle (requires ICC-CE software) [3].
There are 2 pumps needed, one for the gradient run and another (higher flow rate and isocratic) for regeneration [4]. This configuration requires a TrioVS Valve [5]. All of the valves must be controlled by the Standard LEAP cycle.
LEAP can not control the MS Selector valve as part of the cycle.
For other cost/time saving measures consider:
- LEAP offers multiple choices of Valve Self Wash Stations to aid in cleaning the valve [6]
- Summary of LC Multi Valve Applications [7]
- LEAP Shell Software and application for custom injections and scheduling [8]
Contact LEAP
For detailed information on In-line Sample Concentration or Filtration please contact LEAP Technologies