M-005 Dual Channel Parallel Injection - LEAP Shell "(M-Fab)"
From LEAP
Dual Channel Parallel Injections with LEAP Shell "M-Fab" | |
Application Type | |
SPECIAL | |
Application ID | |
M-005 | |
Description | |
High Throughput LC injections alternating onto two analytical columns. |
Overview
This configuration provides short cycle times by limiting the acquisition time to just the peaks of interest and regenerating the columns during the acquisition. It uses LEAP Shell Scheduling Software[1] - this application is integrated withAnalyst® Software[2] from Applied Biosystems Inc® . There is a single sample list and allows multiplexing [3] of 2 separate HPLC systems into one mass spectrometer.
- LEAP Shell - M-Fab application integrated with Analyst with supported pumps.
If the peaks of interest come off together in the middle of the gradient (as shown below) then it is possible to utilize the front cut and back cut time to increase throughput.
If injections are staggered in the following way, there is a potential for up to 100% gain:
Hardware Requirements
- TrioVS multiple valve system is required in addition to the standard injection valve.
Contact LEAP
For additional information about this technique please contact LEAP Technologies for detailed information