M-001 Dual Channel Serial Injection - Analyst with ICC-CE

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LC Column Switching & Regeneration
Application Type
  SPECIAL
Application ID
  M-001
Description
  LC Column Switching & Regeneration.

Overview

This configuration allows the regeneration of one of the analytical columns while the other one is engaged - giving greater efficiency and higher throughput. This is run directly from within Analyst using a Standard LEAP Cycle (requires ICC-CE software).

There are 2 pumps needed, one for the gradient run and another (higher flow rate and isocratic) for regeneration. This configuration requires a 6 port valve for sample loading and a 10 port valve for column switching.
Both valves must be controlled by the Standard LEAP cycle. LEAP can not control the MS Selector valve as part of the cycle.

Plumbing of valve diagram showing flow for each selected column with the regeneration of the analytical column while the other is engaged with the LCMS system
Plumbing of valve diagram showing flow for each selected column with the regeneration of the analytical column while the other is engaged with the LCMS system
Key Benefits
Saving of Reagent time(Back cut)
Increase throughput at little cost
Control is within Analyst
Compliance not affected
GLP Compliant


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Contact LEAP

For additional information about this technique please contact LEAP Technologies for detailed information

Keyword: Analyst Software, ICC-CE, PAL, 10 port valve, selector valve, injector valve, gradient pump, regeneration pump,back cut, peaks of interest, GLP

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