Forced Degradation - Dual PAL under LEAP Shell

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Reaction mixtures are prepared and then incubated at 4 different temperatures. Over a period of time, samples are taken from each batch and injected to the HPLC to determine analyte stability.  
Reaction mixtures are prepared and then incubated at 4 different temperatures. Over a period of time, samples are taken from each batch and injected to the HPLC to determine analyte stability.  
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Time intervals are determined in theMethod. Batches can run from just a few hours to several days.
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Time intervals are determined in the Method. Batches can run from just a few hours to several days.
[[Image:Forced_Degredation_Workflow.png]]
[[Image:Forced_Degredation_Workflow.png]]

Revision as of 00:33, 4 April 2009

Reaction mixtures are prepared and then incubated at 4 different temperatures. Over a period of time, samples are taken from each batch and injected to the HPLC to determine analyte stability.

Time intervals are determined in the Method. Batches can run from just a few hours to several days.

Image:Forced_Degredation_Workflow.png

Experimental Workflow


Image:Forced_Degredation_PAL.png

PAL System configuration


Project Ref: LS-T1006


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