Discovery of Biomarkers for Endometrial Carcinoma
From LEAP
Purpose: Discovering biomarkers for endometrial carcinoma rapidly by direct profiling of proteins in tissue sections.
Methods: nano-scale MALDI-Spotting and MALDI QqTOF mass spectrometry.
Results: Five up-regulated protein markers for endometrial carcinoma were discovered with the new tool.
Discovery of Biomarkers for Endometrial Carcinoma by Direct Profiling of Proteins in Tissue Sections Using Selective MALDI-SPOTTING and MALDI MS
Jingzhong Guo (1); Muntajib Alhaq (2); Leroi V. DeSouza (1); Gordon Nye (3); Werner Martin (3); Alexander D. Romaschin (4); Terence J. Colgan (2); K..W. Michael Siu (1) 1 York University, Toronto, ON, Canada; 2 Mount Sinai Hospital, Toronto, ON, Canada; 3 LEAP Technologies, Inc., Carrboro, NC; 4 Toronto General Hospital, Toronto, ON, Canada
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