Category:DBS

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(As Seen at the CPSA October 2010)
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LEAP Technologies will present '''"Novel Walk Away Automation for DBS sample extraction from 4-Spot Cards to LC-MS"''' at the CPSA 2010 annual meeting being held at the Bucks County Sheraton Hotel, 400 Oxford Valley Road, Langhorne, Pennsylvania 19047. <br>To see information about this Dried Blood Spot system please visit us on Tuesday, October 19th from 1 - 3:30pm at our Poster.<br><br>The Dry Blood Spot (DBS) technique of eluding the blood sample from filter paper cards still lacks simple, reliable and inexpensive automation. There are approx.100 methods/applications known for these sample carrier DBS cards. In many such areas automation would be a tremendous benefit. It would not only be labor saving, but also decrease handling, which means less errors and more consistency in getting the samples introduced into a separation and then the analytical system.<br>
LEAP Technologies will present '''"Novel Walk Away Automation for DBS sample extraction from 4-Spot Cards to LC-MS"''' at the CPSA 2010 annual meeting being held at the Bucks County Sheraton Hotel, 400 Oxford Valley Road, Langhorne, Pennsylvania 19047. <br>To see information about this Dried Blood Spot system please visit us on Tuesday, October 19th from 1 - 3:30pm at our Poster.<br><br>The Dry Blood Spot (DBS) technique of eluding the blood sample from filter paper cards still lacks simple, reliable and inexpensive automation. There are approx.100 methods/applications known for these sample carrier DBS cards. In many such areas automation would be a tremendous benefit. It would not only be labor saving, but also decrease handling, which means less errors and more consistency in getting the samples introduced into a separation and then the analytical system.<br>
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The poster goes through the work flow of the automation approach step by step. The experience with hardware and software so far will be reviewed, including experience with the built-in internal standard addition. The SCAP DBS has patent pending technology applied and is simple to use. The approach of eluting the dry blood sample off the card directly to a multi-column system by-passes all manual and cumbersome treatment steps of the sample cards. First results from needed cycle times and throughput will be presented. Beta test results with analytical data compared to the traditional manual method will also be shown
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The poster goes through the work flow of the automation approach step by step. The experience with hardware and software so far will be reviewed, including experience with the built-in internal standard addition. The SCAP DBS has patent pending technology applied and is simple to use. The approach of eluting the dry blood sample off the card directly to a multi-column system by-passes all manual and cumbersome treatment steps of the sample cards. First results from needed cycle times and throughput will be presented. Beta test results with analytical data compared to the traditional manual method will also be shown.
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LEAP provides automated workstation instrumentation solutions based on the LEAP CTC PAL X, Y, Z syringe only autosampler robot from LEAP Technologies. This extremely flexible, precise, and adaptable liquid handling robotic platform is available in a variety of lengths and options depending on the requirements of your sample preparation and injections for your UHPLC, LC or GC chromatography.LEAP offers full support and service for the PAL platform in addition to being able to write custom macros, cycles, and scheduling to your applications. Please contact LEAP Technologies on how we can help you get maximized throughput with flexible pipetting automation solutions.
LEAP provides automated workstation instrumentation solutions based on the LEAP CTC PAL X, Y, Z syringe only autosampler robot from LEAP Technologies. This extremely flexible, precise, and adaptable liquid handling robotic platform is available in a variety of lengths and options depending on the requirements of your sample preparation and injections for your UHPLC, LC or GC chromatography.LEAP offers full support and service for the PAL platform in addition to being able to write custom macros, cycles, and scheduling to your applications. Please contact LEAP Technologies on how we can help you get maximized throughput with flexible pipetting automation solutions.
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=== Contact LEAP ===
=== Contact LEAP ===
{{contact|topic=LEAP and the PAL Platform}}
{{contact|topic=LEAP and the PAL Platform}}
Keywords: SCAP, Dried Blood Spot,DBS, online extraction, automated sample extraction platform for online LC-MS/MS bioanalysis, sample card, automated, placement, DBS integrated sample processing, fully automated, optimized extraction of DBS, simplified method development by online extraction, fully automated process saves time and labor costs, no need for additional consumables or centrifuge / filtration, PAL, multiple clamp adapters, LEAP, CTC, HTS, HTS, HTX, Drug metabolism (DM), pharmacokinetic (PK) and toxicokinetic (TK) studies, DMPK, practical solution to processing after with shipping and storing blood samples that require controlled handling and frozen transportation and storage, systems that can prepare and process large quantities of Dried Blood Spot (DBS) samples for LC/MS/MS analysis
Keywords: SCAP, Dried Blood Spot,DBS, online extraction, automated sample extraction platform for online LC-MS/MS bioanalysis, sample card, automated, placement, DBS integrated sample processing, fully automated, optimized extraction of DBS, simplified method development by online extraction, fully automated process saves time and labor costs, no need for additional consumables or centrifuge / filtration, PAL, multiple clamp adapters, LEAP, CTC, HTS, HTS, HTX, Drug metabolism (DM), pharmacokinetic (PK) and toxicokinetic (TK) studies, DMPK, practical solution to processing after with shipping and storing blood samples that require controlled handling and frozen transportation and storage, systems that can prepare and process large quantities of Dried Blood Spot (DBS) samples for LC/MS/MS analysis

Revision as of 22:42, 11 October 2010

As Seen at LEAP



DBS Automated PAL

As Seen at the CPSA October 2010




LEAP Technologies will present "Novel Walk Away Automation for DBS sample extraction from 4-Spot Cards to LC-MS" at the CPSA 2010 annual meeting being held at the Bucks County Sheraton Hotel, 400 Oxford Valley Road, Langhorne, Pennsylvania 19047.
To see information about this Dried Blood Spot system please visit us on Tuesday, October 19th from 1 - 3:30pm at our Poster.

The Dry Blood Spot (DBS) technique of eluding the blood sample from filter paper cards still lacks simple, reliable and inexpensive automation. There are approx.100 methods/applications known for these sample carrier DBS cards. In many such areas automation would be a tremendous benefit. It would not only be labor saving, but also decrease handling, which means less errors and more consistency in getting the samples introduced into a separation and then the analytical system.
The poster goes through the work flow of the automation approach step by step. The experience with hardware and software so far will be reviewed, including experience with the built-in internal standard addition. The SCAP DBS has patent pending technology applied and is simple to use. The approach of eluting the dry blood sample off the card directly to a multi-column system by-passes all manual and cumbersome treatment steps of the sample cards. First results from needed cycle times and throughput will be presented. Beta test results with analytical data compared to the traditional manual method will also be shown.



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LEAP strives to find total solutions for analytical lab automation by automating analytical processes for small and large molecules in extracted liquids, solids, and recently in human, animal and plant tissues. We provide the precise robotics and efficient sample prep required by modern measurement techniques such as MALDITOF mass spectroscopy. Our newest specialty customization of CTC Analytics’ PAL features small workstations that can perform complex liquid handling tasks including HPLC-Purification, SPE, filtration, weighing, heating and stirring. They can be configured as stand alone units or integrated for “just in time” sample prep for LC-MS or GC-MS analysis.
LEAP provides automated workstation instrumentation solutions based on the LEAP CTC PAL X, Y, Z syringe only autosampler robot from LEAP Technologies. This extremely flexible, precise, and adaptable liquid handling robotic platform is available in a variety of lengths and options depending on the requirements of your sample preparation and injections for your UHPLC, LC or GC chromatography.LEAP offers full support and service for the PAL platform in addition to being able to write custom macros, cycles, and scheduling to your applications. Please contact LEAP Technologies on how we can help you get maximized throughput with flexible pipetting automation solutions.

Contact LEAP

Contact LEAP

For additional information about LEAP and the PAL Platform, please contact LEAP Technologies.

Keywords: SCAP, Dried Blood Spot,DBS, online extraction, automated sample extraction platform for online LC-MS/MS bioanalysis, sample card, automated, placement, DBS integrated sample processing, fully automated, optimized extraction of DBS, simplified method development by online extraction, fully automated process saves time and labor costs, no need for additional consumables or centrifuge / filtration, PAL, multiple clamp adapters, LEAP, CTC, HTS, HTS, HTX, Drug metabolism (DM), pharmacokinetic (PK) and toxicokinetic (TK) studies, DMPK, practical solution to processing after with shipping and storing blood samples that require controlled handling and frozen transportation and storage, systems that can prepare and process large quantities of Dried Blood Spot (DBS) samples for LC/MS/MS analysis

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