LC Column Switching and Regeneration

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This configuration allows the regeneration of one of the analytical columns while the other one is engaged - giving greater efficiency and higher throughput. This can be run directly from within '''Analyst''' using a custom Cycle (requires ICC-CE).
This configuration allows the regeneration of one of the analytical columns while the other one is engaged - giving greater efficiency and higher throughput. This can be run directly from within '''Analyst''' using a custom Cycle (requires ICC-CE).
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There are 2 pumps needed, one for the gradient run and another (higher flow rate and isocratic) for regeneration. This configuration requires a 6 port valve for sample loading and a 10 port valve for column switching.  
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There are 2 pumps needed, one for the gradient run and another (higher flow rate and isocratic) for regeneration. This configuration requires a 6 port valve for sample loading and a 10 port valve for column switching. Both valves must be controlled by the custom cycle. LEAP can not control the MS Selector valve as part of the cycle.

Revision as of 15:25, 12 February 2009

LC Column Switching & Regeneration
Application Type
  SPECIAL
Application ID
  M-001
Description
  LC Column Switching & Regeneration.

Overview

This configuration allows the regeneration of one of the analytical columns while the other one is engaged - giving greater efficiency and higher throughput. This can be run directly from within Analyst using a custom Cycle (requires ICC-CE).

There are 2 pumps needed, one for the gradient run and another (higher flow rate and isocratic) for regeneration. This configuration requires a 6 port valve for sample loading and a 10 port valve for column switching. Both valves must be controlled by the custom cycle. LEAP can not control the MS Selector valve as part of the cycle.


Plumbing diagram showing flow for each selected column
Plumbing diagram showing flow for each selected column


Image:key_Benefits2.png‎


Image:Restrictions.png‎

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